Expression of Apoptotic Protease Activating Factor-1 in adenoid cystic carcinoma of the salivary glands and its clinicopathological relevance
نویسندگان
چکیده
منابع مشابه
Immunohistochemical Assessment of Ki-67 Expression in Adenoid Cystic Carcinoma of the Salivary Glands
Objective Adenoid cystic carcinoma (ACC) is a rare malignant tumor originating from the salivary glands. It’s rather bland histological appearance that masks its ultimate biological aggressiveness. Evaluation of cell cycle and mitoses have been useful in predicting malignancy in many tumors. Ki-67 antigen is a human nuclear antigen that presents during all active phases of cell cycle. The aim ...
متن کاملAdenoid cystic carcinoma of the salivary glands.
Eighty-two patients with adenoid cystic carcinoma treated by a radical course of radiotherapy are reviewed. In 44 cases the tumour arose in the major salivary glands and, of these, 77% had an incomplete surgical excision and 23% had only a tumour biopsy before radiotherapy. Thirty-eight tumours arose in the minor salivary glands and, of these, 18% had an incomplete surgical excision and 82% a b...
متن کاملImmunohistochemical Study of HER2/neu Overexpression in Adenoid Cystic Carcinoma of Salivary Glands
Background and Objectives: Adenoid cystic carcinoma (ACC), the most common malignant tumor of submandibular and minor salivary glands, is characterized by a high rate of local recurrence and distant hematogenous metastasis and tendency to invade peripheral nerves. In spite of radiotherapy and surgical treatment, the long-term prognosis is dismal. Today, many studies are being conducted using...
متن کاملExpression of MYB protein and its clinicopathological significance in adenoid cystic carcinoma of salivary gland
Objective: Recent studies revealed the existence of ectopic gene at t(6;9)(q22-23;p23-24) in adenoid cystic carcinoma (ACC), resulting in MYB-NFIB fusion gene formation. In this study, we discuss the expression of MYB of ACC in salivary gland and its clinicopathological significance. Methods: We examined 98 samples of salivary gland adenoid cystic carcinoma and 68 samples of salivary non-ACC ne...
متن کاملimmunohistochemical assessment of ki-67 expression in adenoid cystic carcinoma of the salivary glands
objective adenoid cystic carcinoma (acc) is a rare malignant tumor originating from the salivary glands. it’s rather bland histological appearance that masks its ultimate biological aggressiveness. evaluation of cell cycle and mitoses have been useful in predicting malignancy in many tumors. ki-67 antigen is a human nuclear antigen that presents during all active phases of cell cycle. the aim o...
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ژورنال
عنوان ژورنال: Military Medical and Pharmaceutical Journal of Serbia
سال: 2020
ISSN: 0042-8450,2406-0720
DOI: 10.2298/vsp201026130d